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Failure of Apoptosis and Cancer Metastasis (Biotechnology Intelligence Unit) Hardcover - 1998

by Glinsky, Gennadi V


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This book summarizes recent reports on adhesion-dependent regulation of apoptosis. The author discusses data indicating that highly metastatic cancer cells exhibit a superior survival ability and resistance to apoptosis induced by diverse external signals. He also shows that increased survival of metastatic cancer cells compared to nonmetastatic or poorly metastatic cells is associated with their enhanced galectin-mediated homotypic aggregation and dysfunction of adhesion-dependent regulation of apoptosis. Profound deficiency of two major apoptosis execution mechanisms has been identified as a main characteristic of apoptosis failure in metastatic cancer cells.

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  • Title Failure of Apoptosis and Cancer Metastasis (Biotechnology Intelligence Unit)
  • Author Glinsky, Gennadi V
  • Binding Hardcover
  • Edition 1st
  • Pages 178
  • Language ENG
  • Publisher Springer
  • Date 1998
  • ISBN 9783540645603
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Failure of Apoptosis and Cancer Metastasis

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Springer, 1998. Underlining/marginalia; cover very lightly rubbed, corners very barely rubbed, bottom corner front board ever-so-slightly bumped, top spine end very barely bumped, bottom spine end lightly bumped; six pages with underlining/marginalia in black pen in preface and in first two pages of chapter one; binding tight; cover, edges, interior intact and clean except as noted.. hardcover. Good.
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