AUTOGRAPH DOCUMENT PENNED ON VELLUM & SIGNED BY GEORGE SMITH, OUTLINING "THE SCHEDULE" which is referred to in his "LETTERS PATENT" for "HIS IMPROVEMENT IN MEDICINE ENTITLED 'ANTI-DYSPEPTIC PILLS'."

[August 11, 1821]. [1821]., [1821].. Good. - Folio, 13-3/4 inches high by 11-1/4 inches wide. Over 250 words penned on heavy creamy white vellum listing the ingredients and outlining the dosage and prescribed use for George Smith's "Anti-Dyspeptic Pills". Likely meant to accompany the actual patent application or "Letters Patent", the document asserts that this is "The Schedule referred to in these Letters Patent, and making part of the same, containing a description in the words of the said George Smith himself of his improvement in Medicine entitled 'Anti Dyspeptic Pills'...." George Smith then proceeds to list the ingredients with quantities measured in drachms, grains and scruple, with the exception of the syrup of liquorice for which he recommends using a "sufficient quantity to make the whole into a mass for pills...." The ingredients appear to consist of aloes, gamboge, rhubarb, charcoal, gum myrrh, and Oil of carui (i.e. caraway) which are to be mixed with the syrup of liquorice, the whole to be divided into pills of five grains each. Smith then elaborates, describing dosage and the desired results. Signed in full by George Smith at bottom right, with the signatures of two witnesses, Oliver Hull and Gabriel Winter, penned at bottom left. The document is stained & browned along the edges with some spotting or foxing throughout. Folded once horizontally and twice vertically. Good.

The original patent to which George Smith refers in this document was sold at auction in 1998 and is now in the collection of The Gilder Lehrman Institute of American History.