Breakthrough : Elizabeth Hughes, the discovery of insulin, and the making of a medical miracle / Thea Cooper and Arthur Ainsberg

New York : St. Martin's Press, 2010. First Edition. Hardback. An exceptional copy; fine in an equally fine dust wrapper. Particularly and surprisingly well-preserved; tight, bright, clean and especially sharp-cornered. Literally as new.; 8vo 8"" - 9"" tall; 306 pages; Physical description; viii, 306 pages, 8 unnumbered pages of plates : illustrations, portraits ; 25 cm. ContentsChrist Church Cranbrook, Bloomfield Hills, Michigan, 1981 -- Fifth Avenue, New York City, April 1919 -- Breakfast room of the home of Charles Evans Hughes, New York City, April 1919 -- Library of the home of Charles Evans Hughes, New York City, April 1919 -- New York City, April 1919, later that afternoon -- Toronto, Canada, and Cambrai, France, 1917-1918 -- War, peace, and politics, 1914-1918 -- Glen Falls, New York, April 1920 -- Idea of the Physiatric Institute, May 1920 -- Banting's house in London, Ontario, October 30-31, 1920 -- Toronto or bust, October 1920 to April 1921 -- Presidential politics, 1916 and 1920 -- Physiatric Institute, Morristown, New Jersey, 1921 -- Washington, D.C., and Boston, New York, March to September 1921 -- Washington Conference, November 12, 1921, to February 6, 1922 -- Physiatric Institute, Morristown, New Jersey, November 1921 -- University of Toronto, September to December 1921 -- Crossroads of America, Indianapolis, Indiana, 1919-1921 -- American Physiological Society Meeting, New Haven, Connecticut, December 28-30, 1921Success and failure, the University of Toronto, January, 1922 -- Failure and success, the University of Toronto, February to April 1922 -- Honeymoon cottage, Hamilton, Bermuda, January to July 1922 -- Parents, partners, and pancreases, Indianapolis and Toronto, April to August 1922 -- Fame and famine, Summer 1922 -- Four trunks, Washington, D.C., August 1922 -- Escape from Morristown, August 1922 -- Transformation begins, Toronto, August to November 1922 -- Crossing the line aboard the SS Pan America, August to September 1922 -- Fate, fortune, and forgetting, September to December 1922 -- Nobel Prize and beyond -- Emergence of Elizabeth Gossett. Summary; Written with authentic detail and suspense, and featuring walk-ons by William Howard Taft, Woodrow Wilson, and Eli Lilly himself, among many others, ""Breakthrough"" relives the heartwarming true story of the discovery of insulin. It is 1919 and Elizabeth Hughes, the eleven-year-old daughter of America's most-distinguished jurist and politician, Charles Evans Hughes, has been diagnosed with juvenile diabetes. It is essentially a death sentence. The only accepted form of treatment - starvation - whittles her down to forty-five pounds skin and bones. Miles away, Canadian researchers Frederick Banting and Charles Best manage to identify and purify insulin from animal pancreases - a miracle soon marred by scientific jealousy, intense business competition and fistfights. In a race against time and a ravaging disease, Elizabeth becomes one of the first diabetics to receive insulin injections - all while its discoverers and a little known pharmaceutical company struggle to make it available to the rest of the world. Subjects; Gossett, Elizabeth Hughes 1907-1981 - Health. 20th century. Medicine - History - 20th century. Insulin - history. Diabetes Mellitus, Type 1. Diabetes Mellitus, Type 1 - drug therapy. Diabetes Mellitus, Type 1 - history. Drug Discovery - history.