Hiv-1 Integrase: Mechanism and Inhibitor Design Hardcover - 2011 - 1st Edition
by Nouri Neamati (Editor); Binghe Wang (Editor)
From the rear cover
Provides the Foundation Needed to Design Effective HIV-1 Integrase Inhibitors
Around the world, scientists have been working for years with the goal of designing effective HIV-1 integrase inhibitors in the battle against AIDS. This book reviews all their latest research findings on both inhibitor design and the mechanisms of action of HIV-1 integrase. Chapters have been contributed by leading pioneers in the field from North America, Europe, and Asia. These contributions represent not only a thorough review of the current literature, but also the authors' firsthand experience in drug development and design. Coverage includes such topics as:
-
Integrase mechanism, structure, and function
-
HIV-1 integrase-DNA interaction
-
Host factors affecting provirus stability and silencing
-
Role of metals in HIV-1 integrase inhibitor design
-
Historic perspectives, challenges, and future opportunities
As the first publication to comprehensively examine HIV-1 integrase, this book is essential reading for anyone involved in inhibitor drug discovery.
-
Integrates chemical, biochemical, and biological approaches, enabling readers to take full advantage of a promising target enzyme for combating HIV and retroviruses
-
Illustrates rational drug design for a complex drug target with plenty of step-by-step examples
-
Addresses drug design issues from a variety of perspectives to help readers understand both the challenges and opportunities of developing a successful HIV-1 integrase inhibitor
This book fills an important gap in the review literature, offering a valuable introduction to the field for scientists who need to collaborate with researchers in several disciplines in order to design drugs that effectively target HIV-1 integrase.
Details
- Title Hiv-1 Integrase: Mechanism and Inhibitor Design
- Author Nouri Neamati (Editor); Binghe Wang (Editor)
- Binding Hardcover
- Edition number 1st
- Edition 1
- Pages 528
- Volumes 1
- Language ENG
- Publisher Wiley
- Date 2011-09
- Illustrated Yes
- Features Bibliography, Illustrated, Index
- ISBN 9780470184745 / 0470184744
- Weight 3.2 lbs (1.45 kg)
- Dimensions 11 x 8.3 x 1.3 in (27.94 x 21.08 x 3.30 cm)
-
Themes
- Aspects (Academic): Medical/Medicine Aspects
- Library of Congress subjects Drug Design, Antiviral agents
- Library of Congress Catalog Number 2010043285
- Dewey Decimal Code 616.979
More Copies for Sale
HIV-1 INTEGRASE: MECHANISM AND INHIBITOR DESIGN (HB)
by NEAMATI
- Used
- very good
- Condition
- Used - Very Good
- ISBN 10 / ISBN 13
- 9780470184745 / 0470184744
- Quantity Available
- 1
- Seller
-
Indianapolis, Indiana, United States
- Item Price
-
A$245.05A$19.60 shipping to USA
Show Details
HIV-1 Integrase
- New
- Hardcover
- Condition
- New
- Binding
- Hardcover
- ISBN 10 / ISBN 13
- 9780470184745 / 0470184744
- Quantity Available
- 3
- Seller
-
Woodside, New York, United States
- Item Price
-
A$276.92A$6.18 shipping to USA
Show Details
HIV1 Integrase Mechanism and Inhibitor Design
by Neamati, Nouri/ Wang, Binghe
- New
- Hardcover
- Condition
- New
- Binding
- Hardcover
- ISBN 10 / ISBN 13
- 9780470184745 / 0470184744
- Quantity Available
- 1
- Seller
-
Exeter, Devon, United Kingdom
- Item Price
-
A$366.80A$19.38 shipping to USA