Transgenic and Knockout Models of Neuropsychiatric Disorders Hardcover - 2006
by Gene S. Fisch (Editor); Jonathan Flint (Editor)
From the rear cover
Neuroscientists are now establishing meaningful genotype-phenotype relationships for complex neurobehavioral and neuropsychiatric disorders and even creating animal models for these dysfunctions. These developments have made it imperative to know when such transgenic and knockout models are valid for the human disorders they represent. In Transgenic and Knockout Models of Neuropsychiatric Disorders, a panel of leading researchers comprehensively assesses how and whether the genetic abnormalities produced from these models manifest the neuropsychiatric disorders to which they correspond. The authors focus on transgenic and knockout models of neurocognitive dysfunction and neuropsychiatric dysfunction. The discussion of neurobiological problems covers mental retardation, polyglutamate, as well as speech disorders, and disorders that involve cognitive, social, speech, and language dysfunction. The neuropsychiatric dysfunctions examined include psychosis and schizophrenia, anxiety, depression, and bipolar disorder. Timely introductory articles debate the alleged continuity of species of human and infrahuman behavior (Darwin), the utility of infrahuman animals in understanding human behavior and psychiatric disease, and the suitability of nonhuman models of complex neuropsychiatric dysfunctions involving language.
Comprehensive and systematic, Transgenic and Knockout Models of Neuropsychiatric Disorders offers a clear assessment of whether genetic abnormalities produced from infrahuman models manifest the neuropsychiatric disorders to which they correspond in humans and how best they may be used to carry out successful research today.
Details
- Title Transgenic and Knockout Models of Neuropsychiatric Disorders
- Author Gene S. Fisch (Editor); Jonathan Flint (Editor)
- Binding Hardcover
- Edition U. S. EDITION
- Pages 296
- Volumes 1
- Language ENG
- Publisher Humana
- Date 2006-03-01
- Illustrated Yes
- Features Bibliography, Illustrated, Index, Table of Contents
- ISBN 9781588295071 / 1588295079
- Weight 1.37 lbs (0.62 kg)
- Dimensions 9.18 x 6.3 x 0.84 in (23.32 x 16.00 x 2.13 cm)
- Library of Congress subjects Psychology, Experimental, Mental Disorders - physiopathology
- Library of Congress Catalog Number 2005020469
- Dewey Decimal Code 616.8
Media reviews
Citations
- Scitech Book News, 06/01/2006, Page 75
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