Kinase Drug Discovery Hardcover - 2012 - 1st Edition
by Richard A. Ward (Editor); Frederick Goldberg (Editor)
Although there have been a number of reviews/publications on kinase research, this book fills a gap in the literature by considering the current and future opportunities and challenges in targeting this important family of enzymes. The book is forward-looking and identifies a number of hot topics and key areas for kinase drug discovery over the coming years.
From the rear cover
Kinase drug discovery remains an area of significant interest across the pharmaceutical industry and academia. There are currently 13 FDA-approved small molecule drugs and over 500 small molecules in active development targeting kinases. These agents have delivered significant benefits to patients that can be measured in life extension or improvement in the quality of life in diseases like cancer and inflammation. The kinase family has therefore been a rich source of new targets and opportunities for the pharmaceutical industry but has also presented significant and unique challenges. Although there have been a number of books on kinase research, this book focuses on the future opportunities and challenges, rather than on case studies of specific targets. The editors have also aimed to cover broad themes on a number of hot topics in current kinase drug discovery. Highly respected authors in the field have been identified with a combined drug discovery experience of over 200 years. Areas covered include an insight into how medicinal chemistry has been able to exploit this unique target class, along with reflections on the varied mechanisms of kinase inhibitors. Also addressed is resistance to kinase inhibition caused by amino acid mutations, non-protein kinases and applications beyond the human kinome into parasitic diseases. Modern approaches to finding kinase leads and reflections on how the field may progress over coming years are also described. This book will be of great interest to pharmaceutical scientists, biologists and medicinal chemists working in drug discovery and drug development.
Details
- Title Kinase Drug Discovery
- Author Richard A. Ward (Editor); Frederick Goldberg (Editor)
- Binding Hardcover
- Edition number 1st
- Edition 1
- Pages 332
- Volumes 1
- Language ENG
- Publisher Royal Society of Chemistry
- Date 2012
- Illustrated Yes
- Features Bibliography, Illustrated, Index, Table of Contents
- ISBN 9781849731744 / 1849731748
- Weight 1.41 lbs (0.64 kg)
- Dimensions 9.41 x 6.4 x 0.91 in (23.90 x 16.26 x 2.31 cm)
-
Themes
- Aspects (Academic): Biotechnology Aspects
- Dewey Decimal Code 615.792
More Copies for Sale
Kinase Drug Discovery
by Richard A Ward, Frederick Goldberg,
- New
- Hardcover
- first
- Condition
- New
- Edition
- 1 ST
- Binding
- Hardcover
- ISBN 10 / ISBN 13
- 9781849731744 / 1849731748
- Quantity Available
- 5
- Seller
-
New Delhi, India
- Item Price
-
A$111.80A$15.32 shipping to USA
Show Details
Kinase Drug Discovery
by Richard A Ward
- New
- Condition
- New
- ISBN 10 / ISBN 13
- 9781849731744 / 1849731748
- Quantity Available
- 1
- Seller
-
New Delhi, India
- Item Price
-
A$126.66A$7.66 shipping to USA
Show Details
KINASE DRUG DISCOVERY (HB 2012)
by RICHARD A.W.
- New
- Condition
- New
- ISBN 10 / ISBN 13
- 9781849731744 / 1849731748
- Quantity Available
- 1
- Seller
-
NEW DELHI, Delhi, India
- Item Price
-
A$137.84A$4.59 shipping to USA
Show Details
KINASE DRUG DISCOVERY (HB 2012)
by RICHARD A.W.
- New
- Condition
- New
- ISBN 10 / ISBN 13
- 9781849731744 / 1849731748
- Quantity Available
- 1
- Seller
-
Sahibabad, India
- Item Price
-
A$140.90A$21.44 shipping to USA
Show Details
Kinase Drug Discovery
by Royal Society of Chemistry Staff
- New
- Hardcover
- Condition
- New
- Binding
- Hardcover
- ISBN 10 / ISBN 13
- 9781849731744 / 1849731748
- Quantity Available
- 1
- Seller
-
Woodside, New York, United States
- Item Price
-
A$150.18A$6.11 shipping to USA
Show Details
Kinase Drug Discovery
- New
- Condition
- New
- ISBN 10 / ISBN 13
- 9781849731744 / 1849731748
- Quantity Available
- 1
- Seller
-
New Delhi, India
- Item Price
-
A$166.73A$7.66 shipping to USA
Show Details
Kinase Drug Discovery
- New
- Condition
- New
- ISBN 10 / ISBN 13
- 9781849731744 / 1849731748
- Quantity Available
- 1
- Seller
-
New Delhi, India
- Item Price
-
A$166.73A$7.66 shipping to USA
Show Details
KINASE DRUG DISCOVERY
- New
- Condition
- New
- ISBN 10 / ISBN 13
- 9781849731744 / 1849731748
- Quantity Available
- 1
- Seller
-
New Delhi, India
- Item Price
-
A$174.74A$7.66 shipping to USA
Show Details
Kinase Drug Discovery (Rsc Drug Discovery)
- New
- Hardcover
- Condition
- New
- Binding
- Hardcover
- ISBN 10 / ISBN 13
- 9781849731744 / 1849731748
- Quantity Available
- 1
- Seller
-
Exeter, Devon, United Kingdom
- Item Price
-
A$294.90A$19.48 shipping to USA
Show Details
KINASE DRUG DISCOVERY (HB 2012)
by RICHARD A.W.
- New
- Condition
- New
- Edition
- USA Edition
- ISBN 10 / ISBN 13
- 9781849731744 / 1849731748
- Quantity Available
- 25
- Seller
-
ROANOKE, Virginia, United States
- Item Price
-
A$387.06A$1.52 shipping to USA