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Challenges in Next Generation Sequencing Technologies and Sequence Assembly

Challenges in Next Generation Sequencing Technologies and Sequence Assembly

Challenges in Next Generation Sequencing Technologies and Sequence Assembly
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Challenges in Next Generation Sequencing Technologies and Sequence Assembly Paperback - 2014

by Helmy, Mohamed/ El-metwally, M.sc, Sara/ Ouda, Osama M

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Springer Verlag, 2014. Paperback. New. 114 pages. 9.00x6.00x0.25 inches.
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Details

  • Title Challenges in Next Generation Sequencing Technologies and Sequence Assembly
  • Author Helmy, Mohamed/ El-metwally, M.sc, Sara/ Ouda, Osama M
  • Binding Paperback
  • Condition New
  • Pages 118
  • Volumes 1
  • Language ENG
  • Publisher Springer Verlag
  • Publication date 2014
  • Illustrated Yes
  • Features Bibliography, Illustrated
  • Bookseller's Inventory # x-149390714X
  • ISBN 9781493907144 / 149390714X
  • Weight 0.43 lbs (0.20 kg)
  • Dimensions 9.21 x 6.14 x 0.28 in (23.39 x 15.60 x 0.71 cm)
  • Themes
    • Aspects (Academic): Science/Technology Aspects
  • Category Science
  • Library of Congress subjects Sequence alignment (Bioinformatics), Sequence Alignment
  • Library of Congress Catalogue Number 2014934694
  • Dewey Decimal Code 570
  • Quantity available 2

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From the publisher

The introduction of Next Generation Sequencing (NGS) technologies resulted in a major transformation in the way scientists extract genetic information from biological systems, revealing limitless insight about the genome, transcriptome and epigenome of any species. However, with NGS, came its own challenges that require continuous development in the sequencing technologies and bioinformatics analysis of the resultant raw data and assembly of the full length genome and transcriptome. Such developments lead to outstanding improvements of the performance and coverage of sequencing and improved quality for the assembled sequences, nevertheless, challenges such as sequencing errors, expensive processing and memory usage for assembly and sequencer specific errors remains major challenges in the field.

This book aims to provide brief overviews the NGS field with special focus on the challenges facing the NGS field, including information on different experimental platforms, assembly algorithms and software tools, assembly error correction approaches and the correlated challenges.

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