GENOMIC PERL: FROM BIOINFORMATICS BASICS TO WORKING CODE Hardback - 2003
by REX A. DWYER,
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- Hardback
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Details
- Title GENOMIC PERL: FROM BIOINFORMATICS BASICS TO WORKING CODE
- Author REX A. DWYER,
- Binding Hardback
- Edition N/A
- Condition New
- Pages 352
- Volumes 1
- Language ENG
- Publisher Cambridge University Press
- Publication date 2003
- Illustrated Yes
- Bookseller's Inventory # USD_9780521801775
- ISBN 9780521801775 / 052180177X
- Weight 1.77 lbs (0.80 kg)
- Dimensions 9.96 x 6.97 x 0.91 in (25.30 x 17.70 x 2.31 cm)
- Category Science
- Library of Congress subjects Bioinformatics, Perl (Computer program language)
- Library of Congress Catalogue Number 2003268666
- Dewey Decimal Code 572.802
- Quantity available 5
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Summary
This introduction to computational molecular biology will help programmers and biologists learn the skills needed to start work in this important, expanding field. The author explains many of the basic computational problems and gives concise, working programs to solve them in the Perl programming language. With minimal prerequisites, the author explains the biological background for each problem, develops a model for the solution, then introduces the Perl concepts needed to implement the solution. The book covers pairwise and multiple sequence alignment, fast database searches for homologous sequences, protein motif identification, genome rearrangement, physical mapping, phylogeny reconstruction, satellite identification, sequence assembly, gene finding, and RNA secondary structure. The concrete examples and step-by-step approach make it easy to grasp the computational and statistical methods, including dynamic programming, branch-and-bound optimization, greedy methods, maximum likelihood methods, substitution matrices, BLAST searching, and Karlin-Altschul statistics. Perl code is provided on the accompanying CD.
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From the publisher
First line
Each of us has observed physical and other similarities among members of human families.