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Glial Cell Function (Paperback) (Progress in Brain Research)

Glial Cell Function (Paperback) (Progress in Brain Research)

Glial Cell Function (Paperback) (Progress in Brain Research)
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Glial Cell Function (Paperback) (Progress in Brain Research) Paperback - 2003 - 1st Edition

by Castellano, Bernardo (Editor)/ Nieto-Sampedro, Manuel (Editor)

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Elsevier Science Ltd, 2003. Paperback. New. 1st edition. 784 pages. 10.50x7.75x1.50 inches.
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Details

  • Title Glial Cell Function (Paperback) (Progress in Brain Research)
  • Author Castellano, Bernardo (Editor)/ Nieto-Sampedro, Manuel (Editor)
  • Binding Paperback
  • Edition number 1st
  • Edition 1
  • Condition New
  • Pages 780
  • Volumes 1
  • Language ENG
  • Publisher Elsevier Science Ltd, USA
  • Publication date 2003
  • Features Bibliography, Index
  • Bookseller's Inventory # __0444514864
  • ISBN 9780444514868 / 0444514864
  • Weight 3.99 lbs (1.81 kg)
  • Dimensions 10.14 x 7.6 x 1.28 in (25.76 x 19.30 x 3.25 cm)
  • Category Medical / Nursing
  • Library of Congress subjects Neuroglia
  • Library of Congress Catalogue Number 2003049354
  • Dewey Decimal Code 611.018
  • Quantity available 1

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From the publisher

Although knowledge of the development and differentiation of glial cells has significantly increased in recent years, there are still many questions unanswered. The first section of the book is devoted to this very active topic and includes contributions on Schwann cells, oligodendrocytes, astroglia and microglia.

The second section of the book covers cellular interactions, the role they play on myelination and remyelination, how these interactions take place and the molecules involved.

The third section of this volume focuses on the interactions of neurons with glial cells and their role in brain function. Neuron-glia cross talk appears to be fundamental for synaptic transmission and several chapters in this section address this topic.

The topic of how glial cells react to brain injury and how they participate in neuroprotection and brain repair is covered in section four of this book. As our knowledge about the molecules involved in the regenerative properties of glia increases, new avenues are open for the use of genetically modified glia with therapeutic purposes.

The final section of the book is devoted to therapeutic approaches to tumours, viral and prion infections. Gene therapy is a promising approach for the treatment of gliomas, one of the most devastating forms of cancer. A chapter on prion diseases and microglia addresses a question of tremendous actuality, since prion diseases in cows is at this moment the major veterinary problem in Europe and has created a considerable social alarm.

First line

Most Schwann cells develop from the neural crest (Le Douarin et al., 1991).

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