Model Systems in Aging Paperback - 2010
by THOMAS NYSTRÇÔM
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- Paperback
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Details
- Title Model Systems in Aging
- Author THOMAS NYSTRÇÔM
- Binding Paperback
- Edition Softcover reprin
- Condition New
- Language ENG
- Publisher Springer
- Publication date 2010
- Bookseller's Inventory # ria9783642056987_inp
- ISBN 9783642056987
- Quantity available 1042
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From the publisher
From the rear cover
Aging is the progressive decline in biological functions over time. This decline targets macromolecules, cells, tissues and, as a consequence, whole organisms. Despite considerable progress in the development of testable hypothesis concerning aging in an evolutionary context, a unifying theory of the molecular/physiological mechanistic causes of aging has not been reached. In fact, is it not clear to what extent aging is a programmed or stochastic process.
This book takes the reader from unicellular bacterial deterioration via senescence in yeast and worms to aging in rodents and humans, allowing a comparative view on similarities and differences in different genetic model systems. The different model systems are scrutinized in the light of contemporary aging hypothesis, such as the free radical and genomic instability theories.