BIBLIO is the largest independent book marketplace in the world, with over 100 million books.

Skip to content

Peptide Nucleic Acids: Methods and Protocols

Peptide Nucleic Acids: Methods and Protocols

Peptide Nucleic Acids: Methods and Protocols Hardback - 2002

by Peter E. Nielsen (Editor)

Add to wish list
  • New
  • Hardback
New

Description

Hardcover. New. New Book; Fast Shipping from UK; Not signed; Not First Edition; Peptide nucleic acids (PNAs) have now existed for slightly more than ten years, with the interest in and applications of this pseudopeptide DNA mimic steadily increasing during the entire period. PNAs have rapidly attracted the attentio
Ask the seller a question Add to wish list
A$200.82
A$15.59 Delivery to USA
Standard delivery: 7 to 12 days
More delivery options
Ships from Ria Christie Collections (Greater London, United Kingdom)
The BIBLIO Guarantee

Details

  • Title Peptide Nucleic Acids: Methods and Protocols
  • Author Peter E. Nielsen (Editor)
  • Binding Hardback
  • Edition U. S. EDITION
  • Condition New
  • Pages 274
  • Volumes 1
  • Language ENG
  • Publisher Humana, USA
  • Publication date 2002-07-23
  • Illustrated Yes
  • Features Bibliography, Illustrated, Index
  • Bookseller's Inventory # ria9780896039766_inp
  • ISBN 9780896039766 / 0896039765
  • Weight 1.31 lbs (0.59 kg)
  • Dimensions 9.22 x 6.2 x 0.94 in (23.42 x 15.75 x 2.39 cm)
  • Category Medical / Nursing
  • Library of Congress subjects DNA - Derivatives, Peptides - Derivatives
  • Library of Congress Catalogue Number 2002020567
  • Dewey Decimal Code 572.8
  • Quantity available 818

About Ria Christie Collections Greater London, United Kingdom

Specialising in: Books, Calendars, Fiction Books, Non- Fiction Books, Textbooks
Biblio member since 2014

Hello We are professional online booksellers. We sell mostly new books and textbooks and we do our best to provide a competitive price. We are based in Greater London, UK. We pride ourselves by providing a good customer service throughout, shipping the items quickly and replying to customer queries promptly. Ria Christie Collections

Terms of Sale:

30 day return guarantee, with full refund including original shipping costs for up to 30 days after delivery if an item arrives misdescribed or damaged.

Browse books from Ria Christie Collections

Reader reviews for Peptide Nucleic Acids: Methods and Protocols

Write a review for this book

There are no reviews for this book yet. Be the first to write a review!

Your review will be anonymous unless you login or create an account first.

Overall rating
Remember: You’re rating the book as a work, not the seller or the condition of the specific copy you purchased!

Important Terms and Guidelines

  • Please focus on the book’s content and context. Also, add any personal comments as to how you enjoyed the book. Substantiate your likes and dislikes. You may make comparisons to other books.
  • Reviews must be at least 140 characters in length.
  • Please do not reveal critical plot elements.
  • This is not a help line. Contact customer support if you need help.
Your review must not include:
  • Obscenities, discriminatory language, or other insulting language not suitable for public domain
  • Advertisements, “spam” content, or references to other products, offers or websites.
  • Email addresses, URLs, phone numbers, physical addresses or other contact information.
  • Overly critical comments about other reviews or reviewers
  • Time-sensitive material (i.e. promotional tours, seminars, lectures, etc.)
  • Availability, price, or alternative ordering/shipping information

From the publisher

Peptide nucleic acids (PNAs) have now existed for slightly more than ten years, with the interest in and applications of this pseudopeptide DNA mimic steadily increasing during the entire period. PNAs have rapidly attracted the attention of scientists from a diversity of fields ranging from (bio)organic and biophysical chemistry to prebiotic evolution, and from molecular biology to genetic diagnostics and drug development. Many of the applications take advantage of the unique properties of PNA--an uncharged pseudopeptide--that distinguish this DNA mimic from more traditional DNA analogs. Rather than trying to create a comprehensive collection of all published methods and protocols involving PNA--many of which have not yet been validated-- I have decided to concentrate on select protocols that are either very well established by several groups around the world, such as PCR-clamping and in situ hybridization, or on new methods that may have broader future impact. Basic methods for PNA oligomer synthesis and analyses have also been included. I am very grateful to those friends and colleagues who have enthusiastically contributed their work, discussions, and writing, and thereby made this book possible. Peter E. Nielsen v Contents Preface. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . v Contributors. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ix IINTRODUCTION 1 PNA Technology Peter E. Nielsen. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3 II CHEMISTRY 2 Solid Phase Synthesisof PNA Oligomers Frederik Beck. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 29 3 Synthesis of PNA-Peptide Conjugates Satish Kumar Awasthi and Peter E. Nielsen. . . . . . . . . . . . . . . . . . 43 4 Parallel Synthesis of PNA-Peptide Conjugate Libraries Satish Kumar Awasthi and Peter E. Nielsen. . . . . . . . . . . . . . . . . .

First line

Peptide nucleic acids (PNA) were originally conceived and designed as sequence-specific DNA binding reagents targeting the DNA major groove in analogy to triplex-forming oligonucleotides.

From the rear cover

Peptide nucleic acid (PNA) technology continues to grow in importance throughout molecular biology, genetic diagnostics, and molecular medicine. In Peptide Nucleic Acids: Methods and Protocols, Peter Eigil Nielsen has assembled a critically evaluated collection of PNA protocols that are either already well established around the world, such as PCR-clamping and in situ hybridization, or that display promise of significant future impact. Basic methods for PNA oligomer synthesis and analysis have also been included. Written by experts with hands-on experience in the methods they describe, these readily reproducible protocols contain detailed step-by-step instructions, tips on avoiding pitfalls and on extending the method to other situations, and introductory material explaining the theory behind the process.
Up-to-date and highly practical, Peptide Nucleic Acids: Methods and Protocols provides for both novice and experienced researchers a thorough and easy introduction to the optimal use of today's PNA technology across a wide variety of fields, including molecular biology, medicinal chemistry, genetic diagnostics, and drug development.

Please wait a moment while we load the requested page.

tracking-